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demonstrated that EC effectively counteracted oxysterol-induced IL-8 overproduction, a key event mediated by the NADPH oxidase/p38 MAPK/NF-B inflammatory signaling cascade, further supporting its anti-inflammatory potential at the intestinal epithelial level ( 3.3 JAK/STAT The JAK/STAT signaling pathway plays a central role in cytokine-mediated immune responses and is often dysregulated in chronic inflammatory diseases (Lv et al., 2024)

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Therapeutic potential of butyrate for treatment of type 2 diabetes
