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Cell 135 , 907918 (2008)

The cardinal features of the disorder, although not always present, are loud snoring with sporadic gasps in sleep associated with daytime sleepiness/fatigue or simply unrefreshed sleep

Aggressive doses and erratic protocols appear to lower SHBG, which is one of the reasons we are not proponents of using high dose transscrotal testosterone cream

BMC Gastroenterol 25:641
