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At the post-translational level, 4-HNE accelerated collagen II degradation and activated MMP13, possibly by post-translational modification [78]

[DOI] [PubMed] [Google Scholar] 14.Boltshauser E, Stocker H, Machler M

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Berberine protects against dopamine depletion and -synuclein upregulation, as reported in previous studies, this finding was correlated with the improvement of the number of normal dopaminergic nerves observed in both groups with preference to BER chitosome group [23, 96]