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To measure glutathione S-transferase (GST) enzymatic activity, the optical density of 10 L of supernatant of liver tissue homogenate, 20 mM GSH, and 100 mM phosphate buffer contained mixture was measured at 340 nm after adding 6 mM NADP + (-nicotinamide adenine dinucleotide phosphate disodium salt, Roche, cat

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Niraparib showed promising activity in preclinical models and phase I clinical trials, achieving its pharmacodynamic target for PARP inhibition in epithelial ovarian cancer, particularly in patients who have responded to platinum-based chemotherapy 167 (Fig

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