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Regarding GI issues, the authors of the study linked them to a ketogenic flu, characterized by diarrhea and cramps [189]

Pracinostat plus azacitidine in older patients with newly diagnosed acute myeloid leukemia: results of a phase 2 study

Wallach, H

encapsulated obeticholic acid (OCA) within a ROS-responsive NP coated with MSCM (MPPFTU@OCA), and found the intravenous administration of MPPFTU@OCA reduced macrophage infiltration, intracellular ROS, and mitochondria-induced apoptosis via the FXR-SHP pathway, alleviating primary sclerosing cholangitis (PSC) [372]
