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Furthermore, E2 supplementation has been found to mitigate the elevated oxidative stress levels induced by CIH significantly and to enhance the activity of antioxidant enzymes, such as zinc/manganese superoxide dismutase and glutathione peroxidase, which protect against oxidative stress-related damage (14, 44, 64, 65)
Plasma homocysteine and severity of atherosclerosis in young patients with lower-limb atherosclerotic disease

Regulation of heme breakdown is tightly linked to cellular and systemic iron homeostasis
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