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This review synthesizes evidence that probiotics mitigate UC through multiple synergistic mechanisms: competitive exclusion to rebalance the microbiota, upregulation of tight junction proteins to restore the intestinal barrier, and bidirectional immunomodulation to restrain excessive inflammation

Gnzler WA, Steffens GJ, Grossmann A et al (1984) The amino-acid sequence of bovine glutathione peroxidase
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