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Even short-term use of ICS can lead to an increased risk of both pneumonia and fractures from bone-thinning
Immunol 198:273546 [DOI] [PMC free article] [PubMed] [Google Scholar] 71.Buck MD, OSullivan D, Klein Geltink RI, Curtis JD, Chang C-H, et al
S-nitrosylation can cause the stabilization and the activation of HIF-1 [99] or, conversely, can interfere with the DNA binding and suppress the transcriptional activity of PPAR [100] and of NF-kB [101]
Understanding which physiological systems and related signaling molecules are impacted, as well as the roles of developmental timing and biological sex on individual outcomes will aid in early diagnosis and therapeutic strategies in ASD
