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An imbalance between the production of ROS and the antioxidant defenses that protect cells has been implicated in the pathogenesis of a variety of diseases, such as cancer, asthma, pulmonary hypertension, and retinopathy

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Inhibition of GPX4 induced rapid and selective lipid ROS accumulation and cell death across a panel of human and murine DLBCL cellular models irrespective of subtype

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