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This guideline was developed by the Guidelines and Protocols Advisory Committee in collaboration with the Provincial Laboratory Medicine Services, and adopted under the Medical Services Act and the Laboratory Services Act

It was previously approved by the FDA for diagnostic evaluation and treatment of pediatric GH deficiency and is now widely used off-label in research and clinical settings to address adult-onset GH insufficiency and age-related hormonal decline

Early assessment can prevent complications and ensure appropriate management of potentially serious conditions

In kidney aging studies, it protected renal tubular epithelial cells, reduced renal inflammation, and improved renal function