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Integrating L-carnitine into treatment regimens for PCOS requires the consideration of both cost-effectiveness and the socioeconomic conditions of patients to ensure broader accessibility and optimal health outcomes

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While, down-regulation of the transporter directly confers resistance against the drug, via decreasing the intracellular platinum concentration ( General Features of ATB 0,+ (SLC6A14) ATB 0,+ is a plasma membrane transporter belonging to the SLC6 family that includes amino acid transporters, neurotransmitter transporters, and osmolyte transporters (Pramod et al., 2013)