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Supporting the idea that copper toxicity rather than deficiency may lead to or exacerbate demyelination comes from a study that examined MS lesions in human MS patients as well as in EAE mice and CPZ mice

A method of preventing gait abnormalities in a patient with Parkinson's disease or of improving or restoring to normal the gait of a patient with Parkinson's disease, comprising the step of administering to said patient an amount of one or more hepatocyte growth factor mimics sufficient to prevent, improve or restore to normal said gait, said one or more hepatocyte growth factor mimics having a general structural formula 1 2 3 where Ri is one of an N-acyl group, a substituted or unsubstituted phenyl, a norleucine group, and an amino acid selected from tyrosine, phenylalanine, aspartic acid, arginine, isoleucine, serine, histidine, glycine, cysteine, methionine, tryptophan, lysine norvaline, ornithine, and s-benzyl cysteine

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[DOI] [PubMed] [Google Scholar] 346.Hart P.H., Lucas R.M., Walsh J.P., Zosky G.R., Whitehouse A.J., Zhu K., Allen K.L., Kusel M.M., Anderson D., Mountain J.A