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10.1093/ijnp/pyaa060 123 Ruiz-PozoV

The brains were harvested and post-fixed in 4% paraformaldehyde, followed by dehydration in 20% sucrose-PBS and then 30% sucrose-PBS

Nitrosylating agents derived from nitric oxide can transiently form S-nitrosothiols (R-SNO), which act as activated intermediates that readily undergo further redox reactions, including disulfide bond formation

Considering some studies, pineal calcification contributes to the reduction of melatonin production in humans that is directly associated with the development of neurodegenerative diseases, such as AD [54, 56, 62]
