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In the pivotal 2018 animal study by Neelakantan et al., systemic treat Mechanism of Action 5-Amino-1MQ inhibits NNMT (nicotinamide N-methyltransferase), an enzyme that catalyzes the N-methylation of nicotinamide using S-adenosylmethionine (SAM) as the methyl donor, producing 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH) as products

Tight glucose control, medications for neuropathic pain, and foot/hand care are key

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(Mohtashami et al., 2022) Epitalon Also known as Epithalon or Epithalone, this peptide has many uses including increasing emotional resilience, acting as an antioxidant, helping to regulate the endocrine system and assisting with cellular repair (Seeds, 2020)