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Tou, Jennifer Panganiban Journal of Pediatric Gastroenterology and Nutrition.2026

The mitochondrial membranes are impermeable to coenzyme A(CoA) esters and long-chain fatty acids, binding of L-carnitine to acetyl groups via carnitine acyltransferase is essential for the shuttle of the acetylated fatty acids into the mitochondria and their subsequent oxidation

Similarly, many forms of secondary carnitine deficiency, including some drug-induced disorders, arise from impaired renal tubular reabsorption

To examine antitumor promotion effects of EGCG and theaflavins at the molecular level, used a JB6 mouse epidermal cell line, a system that has been used extensively as an in vitro model for tumor promotion studies