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To allow for possible receptor-site steric hindrance in the design of this study, we selected both the native enzyme dimer and a single GST subunit for docking simulations

Importantly, circulating HTY metabolites, mainly HTY sulfate and HTY glucuronides, reach plasma concentrations several-fold higher than parent HTY and retain cardiovascular-related bioactivity

37,38 Meanwhile, divalent metal transporter protein 1 (DMT1) accounts for the transfer of ferrous ions to the labile iron pool, in which ferrous ions are easily transported to different cell machinery to participate in the synthesis of DNA synthase, heme and iron-sulfur cluster enzymes

CAG260, and Alistipes sp