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In particular, [ 68 Ga]Ga-NOTA-Nb1053 showed to be able to identify tumor infiltration in the bone marrow before the presence of overt bone damage
Mendias, C
This may be due to liver or kidney disease, or certain cancers and blood disorders: The aetiological profile of high serum cobalamin predominantly encompasses severe disease entities for which early diagnosis is critical for prognosis

The mechanism centers on its role in upregulating growth factors and modulating inflammation at injury sites without systemic immunosuppression