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(2) Moderate levels of exercise-induced reactive oxygen and nitrogen species (ROS/RNS) can support training adaptations but excessive levels can result in muscle damage, inflammation, and reduced physical performance and immune function

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Here we explore these therapeutic approaches, focusing first on strategies that directly influence protein folding and aggregation

In addition, thiamine is known to be involved in the uptake of serotonin and GABA, which, when deficient, leads to cellular abnormalities that affect cerebellar, hypothalamic, and hippocampal activity