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That context shapes how we decide on dose, route, timing, and duration
Pharmacodynamic Drug Interactions (of High Clinical Significance) Warfarin: Interaction: ALC may potentiate warfarins anticoagulant effects Mechanism: Unclear

doi: 10.3389/fphys.2021.682482 140 Del RioDZimettiFCaffarraPTassottiMBerniniFBrighentiFet al
Also, doses of 1000 mg taken two or three times daily seems to work better than doses of 500 mg three times daily