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Description
The PPP shares reactions with the EntnerDoudoroff pathway and Calvin cycle and divides into an oxidative and non-oxidative branch
When opposed to normal cells, one of the most distinguishing characteristics of cancer cells is their constant pro-oxidative state, which can lead to intrinsic oxidative stress [22, 23]
Unlike nuclear DNA, mtDNA lacks protective histones and has limited repair capacity, making it more susceptible to oxidative damage and mutation
Crotty G
