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134 A realworld analysis of the Czech Registry of Monoclonal Gammopathies of DaraRd found no statistically significant benefit to DaraRd in patients with gain(1q21) versus patients who received Rd, with a hazard ratio of 1.33 for PFS by univariable Cox model
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This tryptophan steal diverts serotonin precursors toward neurotoxic kynurenine pathways, driving severe cortical hyperarousal
doi: 10.1002/em.21832
