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Cysteines are among the four most frequently conserved amino acids (together with glycine, proline, and tryptophan) in proteins [31]

While oral liposomal forms are typically fine, inhaled glutathione has been known to trigger bronchospasms (narrowing of the airways) in some people with sensitive lungs

When applied to a peptide sequence designed to interact with the C-terminal domain of the HIV-1 capsid assembly polyprotein (C-CA), this stapling modification resulted in improved binding affinity, cell permeability, and proteolytic stability compared to its unstapled counterpart

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