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7 Clinical outcomes of pharmacotherapy To date, numerous clinical studies including double- or single-blinded randomized clinical trials and split-face studies have been conducted to assess the therapeutic effect of various topical conventional and novel formulations in melasma management as summarized in Table 3
Duncan Macewan Person If we look at this data over time and look at license production over time, this is just the licensed market going back to 2020, split between the adult use or recreational and medicinal sales

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