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This was based on in vitro data showing that the presence of alcohol impacted the pattern of release for TROKENDI XR (higher concentrations sooner and potentially leading to subtherapeutic concentrations later)

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The peptides themselves only work when administered correctly, and mistakes in preparation or timing can undermine an otherwise well-designed protocol

This indicates that Bor-Sch B-Ms can enhance the therapeutic effects on N2a cells and facilitate a greater amount of drugs crossing the BBB into the brain parenchyma[108]