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The Otsu method was then applied for automatic thresholding of the I channel, followed by binarization (Convert to Mask function) to ensure a clear distinction between CMHs and surrounding tissue

Needles below 25 gauge are too wide for comfortable subcutaneous self-injection

B12 supplements come in several forms: Cyanocobalamin: Widely available and stable Methylcobalamin: Active form often used for nervous system support Hydroxocobalamin: Preferred in some cases for slower release Choosing the right form is especially important for patients with histamine intolerance, as tolerance varies

It may be safe to take expired vitamins, but expired medications may not be effective