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Positron Emission Tomography (PET) ligand development for ionotropic glutamate receptors: challenges and opportunities for radiotracer targeting N-methyl-d-aspartate (NMDA), -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) and kainate receptors

Thus, direct NAD + administration may exhibit unique effects compared to NAD + precursors and modulators, warranting further investigation, especially given the rise of wellness and anti-aging clinics offering intravenous NAD + therapy, while clinical evidence is still scarce 119
