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The Childrens Research Institute Metabolomics Core is supported by an award from The Cancer Prevention Research Institute of Texas (CPRIT Core Facilities Support Award RP240494)

Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism

At the initial stages, the traumatic injury (primary injury) only affects the spinal cord mechanically by damaging the blood vessels and cellular membranes, causing ischemia and inflammation

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