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doi: 10.3389/fphar.2021.771459 Received 06 September 2021 Accepted 19 October 2021 Published 04 November 2021 Volume 12 - 2021 Edited by Annabella Vitalone, Sapienza University of Rome, Italy Reviewed by Luis Enrique Gomez-Quiroz, Autonomous Metropolitan University, Mexico Maitane Asensio, University of Salamanca, Spain Updates Copyright 2021 Fu, Wang, Ma, Zhou and Li