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Multiple antioxidant genes are upregulated, including those encoding superoxide dismutase, glutathione-related enzymes, and other protective systems

It is not the active ingredient in any FDA-approved drug product, and there is no United States Pharmacopeia (USP) monograph for either AOD-9604 (free base) or AOD-9604 acetate

The appearance of the vessels was assessed (see also Figure 1) between (1) the last arcade proximal to first ligation (arcade 0) and the first arcade distal to the ligation (or to the previous ligation) (arcade 1) (0-1, Figure 2, Figures 5-8, and Figures 21 and 22)