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BMC Microbiol 26 , 410 (2026)
W.KimS.ParkJ
GLP-1 mediates its effects through binding at a transmembrane receptor (GLP-1R), found on pancreatic cells and CNS neurons
To date, three primary classes of therapeutic agents have been assessed in both animal models and clinical trials: small molecular tyrosine kinase inhibitors, antibodies to IGF-1R, and antibodies to IGF ligands
