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Immune disorders such as Graves disease and lupus

Diabetes 50 : 11101118 Yakar S et al

While direct evidence linking the RARA::RXRA and RARA::RXRG complexes to CCL11 expression in the CNS is currently not well established, it is plausible to speculate that retinoic acid signaling through these complexes could inhibit CCL11 expression in specific brain conditions

They may also use deep tissue massage, water aerobics, or TENS units (transcutaneous electrical nerve stimulation)