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deficiencies of vitamin B12, folate or niacin, and infective causes including cryptococcal meningitis, HIV, Lyme disease, progressive multifocal leukoencephalopathy, subacute sclerosing panencephalitis, syphilis and Whipple's disease
In the yeast and mammalian cytosol, the thioredoxin pathway was considered to be the major reductive pathway with the glutaredoxin/glutathione system having only a back-up or auxiliary role [38, 40]
