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In the context of COVID-19 pathology, neuropsychiatric manifestations, and PCS, mGluR2 could be viewed as a mediator that links the continuum between nociception, pain, negative mood, and depression [230]

Potential application of ICD in glioma targeted therapy In 1893, American orthopedic surgeon William Coley made a serendipitous discovery that postoperative pyogenic streptococcal infections could induce tumor regression in sarcoma patients, thus marking the dawn of tumor immunotherapy

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For instance, while cyclic peptides like CyRL-QN15 gain enzymatic resistance through rigid structures 84 , tripeptides such as GHK maintain therapeutic potency while being more adaptable and versatile in formulation