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SYMPTOMS ADDRESSED BY METHYLCOBALAMIN B-12 INJECTIONS A deficiency in Vitamin B-12 can lead to various health issues, including: Fatigue and weakness Pale or jaundiced skin Neurological symptoms, such as numbness and tingling in extremities Memory loss or cognitive decline Shortness of breath and dizziness Glossitis (inflammation of the tongue) and mouth ulcers B-12 deficiency is common in vegetarians, vegans, older adults, and individuals with gastrointestinal disorders that impair absorption

doi: 10.1200/jco.2010.28.15_suppl.10000 109 RamalingamSSSpigelDRChenDSteinsMBEngelmanJASchneiderCPet al

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Using quantitative realtime ROS assays, it was shown that both the yeast and filamentous forms of can activate ROS production in macrophages and dendritic cells