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2009;1:CD007168

This combined approach effectively disrupted the PD-1/PD-L1 pathway, leading to enhanced pro-inflammatory anti-tumor responses, including heightened infiltration and activity of NK cells and CD8+ cytotoxic T cells, and a decreased frequency of Treg cells

This mainly includes older adults, people with pernicious anemia, people who have had gastrointestinal surgery or have digestive disorders such as celiac disease or Crohns disease, and people who eat little to no animal foods such as vegetarians and vegans

At visits 1 and 5, neurocognitive assessments (Trail Making Test, Block Corsi Test, Subtest Digit Span, Category (Animal) Fluency and Controlled Oral Word Association Test, COWA (FAS test), and Rey Auditory Verbal Learning Test), collection of blood samples, measurement of abdominal circumference and body mass index (BMI) were carried out