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Many other intranasal preparations using specialized delivery systems involving nanoparticles are being assessed in laboratory and sometimes human trials across a range of diseases

Oral pretreatment with liposomal glutathione attenuates reperfusion injury in rabbit isolated hearts
Additionally, mutations in nDNA genes such as succinate dehydrogenase (SDH), fumarate hydratase (FH), isocitrate dehydrogenase 2 (IDH2), and IDH3 in the mitochondrial tricarboxylic acid (TCA) cycle were also observed to result in increasing levels of succinate, fumarate, or 2-hydroxyglutarate [208210]

Onore C, Careaga M, Ashwood P
