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Most site reactions resolve spontaneously within days as technique improves and body adapts

Liquid biopsy is a non-invasive method that enables dynamic monitoring of circulating tumor DNA (ctDNA), providing insights into tumor heterogeneity and genomic alterations across different sites, including the primary tumor and off-target metastatic lesions

Conversely, histone deacetylases (HDACs) remove acetyl groups, leading to chromatin condensation and gene repression

Disruption of NADPH production compromises GSH regeneration, limits GPX4-dependent detoxification of lipid peroxides, and can promote ferroptosis even in the absence of impaired GSH synthesis 152