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Melatonin treatment was found to increase the expression of lamellar protein and radiate alveolar count produced by AEC II, increase the levels of GPX and SOD, and decrease the levels of MDA, implying that melatonin can regulate the oxidative balance, protect pulmonary vascular endothelial cells, and promote alveolarization in hyperoxia-induced lung injury (191)

In patients with T2DM and other metabolic abnormalities, elevated SELENOP levels exacerbate IR and reduce the efficiency of insulin transport into the CNS, thereby compounding metabolic dysfunction and possibly contributing to neurodegenerative processes [224]

But before we hand out choline supplements like prenatal candy, newer research gives us pause