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Description
Although not explicitly studied for pinostrobin, other flavonoids such as pinocembrin are known to interact with transporters such as P-glycoprotein (P-gp) and multidrug resistance proteins, which could potentially play a role in the transport of pinostrobin (75)
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The class of chemical compounds that these transporter proteins can eliminate includes, but is not limited to, anthracyclines, actinomycin D, bisantrene, camptothecins, colchicins, imatinib, methotrexate, mitoxantrone, thiopurines, saquinivir, and even vinca alkaloids [13, 32, 37, 39, 45]
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Molecules 19(11):1906619077 Collier HOJ, Dinnen LC, Johnson CA, Schneide C (1968) The abdominal constriction response and its suppression by analgesic drugs in the mouse
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Hans Selye (1907-1982): Founder of the stress theory