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However, as an individual treatment and in combination with other antineoplastic medicines, curcumin has demonstrated promising effects in the treatment of several cancers: It has an impact on several signaling pathways and can therefore successfully alter both the initiation and progression of certain cancers (Zoi et al., 2021)

60 A demethylnaphthoquinone oxidoreductase then reduces the resulting demethylphylloquinone product to demethylphylloquinol (reaction 9, Figure 2), 61 which is promptly transmethylated by demethylphylloquinone methyltransferase to phylloquinol (reaction 10, Figure 2), 61,62 the reduced form of phylloquinone

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Williams SS, Williams J, Combrinck M, Christie S, Smith AD, McShane R (2009)