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Some participants achieved weight loss of approximately 24% of body weight at 48 weeks approaching levels reported with some bariatric surgical procedures, though no direct head-to-head comparisons have been conducted and long-term durability beyond the trial period remains unknown

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

Interestingly, acetylcholine has been shown to cause both vasoconstriction and vasodilation in coronary vessels

This suggests a general regulatory effect on protein breakdown in skin, helping to prevent both buildup of damaged proteins and excessive proteolysis [10,11]