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Description
Acta 1832 , 17441755 (2013)
Deviations prompt researchers to refine computational parameters, improving predictive accuracy
Notably, ferroptotic cell death, regardless the mechanisms of activation, can be blocked by iron chelators, indicating a central role of iron in the regulation and execution of ferroptosis
However, there are limitations of the rotenone-based model, which are low reproducibility and acute toxicity 30,31
