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Pissimissis, N., Papageorgiou, E., Lembessis, P., Armakolas, A

It is well established that inflammation-related infection is the main cause of UTI recurrence and symptoms [33]
it is also observed in mild to moderate cases

Subsequently the ubiqutinated IB is degraded by the proteosome and this unmasks the DNA binding activity of the p50/RelA heterodimer and also allows it to translocate to the nucleus where it can bind to B sites and activate gene transcription 1, 2, 4, 5
