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Cagrilintides gastric effect is inferred with reasonable confidence from receptor pharmacology, animal data, and its gastrointestinal side-effect profile, but published monotherapy trials did not center on validated gastric-emptying measurements (scintigraphy or breath testing) tracked over time
doi: 10.1038/nrgastro.2017.88
Notably, 5-amino-1MQ treatment did not show a significant impact on the food intake and any observable adverse effects
