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Description
278 These pathways lead to granzyme release, ROS production, 279 and the activation of transcription factors, including STAT3, 280 NF-B, activator protein 1 (AP-1), 281 and cAMP-responsive element-binding protein (CREB), 277 which further contributes to the expression of pro-inflammatory cytokines, co-stimulatory molecules, and complement components
In rare cases, the disease can inflame the brain, spinal cord or other tissues or cause deafness
S.MedaP
Treatment of Chronic Lymphocytic Leukemia and Related Disorders
