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150 In addition to reducing fever and physical pain, acetaminophen has a profound effect on adult brain function, blunting the response to both negative and positive stimuli, including threatening stimuli, 151,152 and reducing behavioral responses to social rejection

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Let's look at what some of these side effect reactions etc that people have from taking B12

Further, the study allowed some use of acetaminophen in all patients, and only involved 3 months of restricted use in the experimental population versus liberal use in a control population