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Indoleamine 2,3-dioxygenase 1 (IDO1), an intracellular enzyme, is involved in the metabolism of the essential amino acid tryptophan in the kynurenine pathway, and IDO1 overexpression promotes the upregulation of PD-1 expression and the infiltration of Tregs [347]
Dupuytrens disease is also known as Dupuytrens contracture
doi:10.1016/j.sleh.2023.02.010
