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The HPA axis of the newborn infant is upregulated towards the time of delivery, leading to a surge in cortisol levels and then a gradual decline after birth 19,24

Because human studies are limited, doctors do not yet have clear data on the peptide's long-term effects, optimal dosing, potential drug interactions, or safety across different patient populations

however, these were predominantly mild to moderate and tended to decrease over time, which aligns with expectations for the GLP-1 receptor agonist class

Other causes of pain and numbness in the thigh such as degenerative disc disease of the lumbar spine can be ruled out by your doctor