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Acknowledgements We are deeply indebted to the participants of the TOPIC trial

Geneenvironment interactions in Alzheimer disease: the emerging role of epigenetics

Between courses, gaps of 3 to 6 months are standard

In a DMBA/TPA two-stage skin carcinogenesis model, overexpression of the skin antioxidant enzymes Gsh-px or Gsh-Px + SOD increases cancer instead of decreasing it [103]
