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Oxidative stress happens when your body is out of balance between free radicals and antioxidants

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Chen J.G., Kensler T.W., Zhu J., Zhu Y.R., Wang J.B., Lu J.H., Muoz A., Groopman J.D

doi: 10.1172/JCI108921

Curcumin is often described as a hormetic compound because it induces an adaptive stress response: it mildly stresses cells in ways that activate Nrf2 and other transcription factors, leading to increased production of antioxidant and cytoprotective proteins (e.g., heme oxygenase-1) that precondition cells against subsequent injuries (77, 78)
